Pitstop 1-25
Pitstop 1-25 Basic information
- Product Name:
- Pitstop 1-25
- Synonyms:
-
- Pitstop 1-25
- Clathrin IN 25
- ClathrinIN25
- Clathrin-IN-25
- Pitstop 1-25, clathrin inhibitor
- CAS:
- 1419321-16-6
- MF:
- C19H14KNO5S
- MW:
- 407.48
- Mol File:
- 1419321-16-6.mol
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Pitstop 1-25 Usage And Synthesis
Description
Clathrin-IN-25 is the most potent clathrin terminal domain-amphiphysin inhibitor reported to date.
Uses
Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC50: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI[1].
References
[1] MacGregor KA, et al. Development of 1,8-naphthalimides as clathrin inhibitors. J Med Chem. 2014 Jan 9;57(1):131-43. DOI:10.1021/jm4015263