sodium 3-[(2-methyl-2-undecyl-1,3-dioxolan-4-yl)methoxy]-1-propanesulfonate Chemical Properties

solubility 

DMSO, water, methanol

form 

Solid

color 

Off-white to light yellow

Appearance

white to off-white foam

sodium 3-[(2-methyl-2-undecyl-1,3-dioxolan-4-yl)methoxy]-1-propanesulfonate Usage And Synthesis

Description

ALS-1 is an acid-Liable surfactant.

Uses

ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain[1][2].

in vivo

References

[1] K?nig S,et al. Sodium dodecyl sulfate versus acid-labile surfactant gel electrophoresis: comparative proteomic studies on rat retina and mouse brain. Electrophoresis. 2003;24(4):751-756. DOI:10.1002/elps.200390090
[2] Norrgran J, et al. Optimization of digestion parameters for protein quantification. Anal Biochem. 2009;393(1):48-55. DOI:10.1016/j.ab.2009.05.050