BODIPY CYCLOPAMINE
BODIPY CYCLOPAMINE Basic information
- Product Name:
- BODIPY CYCLOPAMINE
- Synonyms:
-
- BODIPY CYCLOPAMINE
- [5-[(3,5-DiMethyl-2H-pyrrol-2-ylidene-κN)Methyl]-N-[6-[[2-[(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetraMethylspiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]aMino]-6-oxohexyl]-1H-pyrrole-2-propanaMidato-κN1]difluoro-boron
- 5,5-Difluoro-7-(3-((6-((2-((2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,4,5',6,6a,6b,6',7,7',7a',8,11,11a,11b-hexadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-4'(3a'H)-yl)ethyl)amino)-6-oxohexyl)amino)-3-oxopropyl)-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide
- CAS:
- 334658-24-1
- MF:
- C49H70BF2N5O4
- MW:
- 841.9190064
- Product Categories:
-
- Fluorescent Labels & Indicators
- Inhibitors
- Steroids
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Fluorescent Labels & Indicators, Inhibitors, Steroids, Pharmaceuticals, Intermediates & Fine Chemicals
- Fluorescent Labels and Indicators
- Mol File:
- 334658-24-1.mol
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BODIPY CYCLOPAMINE Chemical Properties
- Melting point:
- 128-130°C
- storage temp.
- Amber Vial, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly)
- form
- Solid
- color
- Red to Brown
- Stability:
- Light Sensitive
- InChIKey
- CQPRECBXTRAUSE-NJOUNXRJNA-N
- SMILES
- C1CC2(C)C3CC4=C(C)C5(O[C@H]6CC(C)CN(CCNC(=O)CCCCCNC(=O)CCc7[n]8[B-](F)(F)[N+]9=C(C)C=C(C)C9=Cc8cc7)C6C5C)CCC4C3CC=C2C[C@H]1O |&1:11,59,r|
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BODIPY CYCLOPAMINE Usage And Synthesis
Chemical Properties
Orange Powder
Uses
Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The Bodipy-Cyclopamine is a fluorescent derivative of Cyclopamine that retains potency in Shh signaling inhibiti
Uses
It is a fluorescent derivative of Cyclopamine that retains potency in Shh signaling inhibition (IC50=150nM).
BODIPY CYCLOPAMINESupplier
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