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GLP-1 receptor agonist 1

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GLP-1 receptor agonist 1 Basic information

Product Name:
GLP-1 receptor agonist 1
Synonyms:
  • 1,2,4-Oxadiazol-5(2H)-one, 3-[(1S,2S)-1-[2-[[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2,3-dihydro-2-oxo-1H-imidazol-1-yl]-2,4,6,7-tetrahydro-4-methyl-5H-pyrazolo[4,3-c]pyridin-5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indol-1-yl]-2-methylcy...
  • LY3502970
  • GLP-1 receptor agonist 1 USP/EP/BP
  • Orforglipron
  • Orforglipron(LY3502970)
  • LY3502970 (Orforglipron)
  • 3-((1S,2S)-1-(5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-3-(3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carbonyl)-1H-indol-1-yl)-2-methylcyclopropyl)-1,2,4-oxadiazol-5(4H)-one
  • OWL 833
CAS:
2212020-52-3
MF:
C48H48F2N10O5
MW:
882.97
Product Categories:
  • 1
Mol File:
2212020-52-3.mol
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GLP-1 receptor agonist 1 Chemical Properties

Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 125 mg/mL (141.57 mM)
form 
Solid
pka
7.33±0.20(Predicted)
color 
Off-white to light yellow
InChIKey
USUWIEBBBWHKNI-BBGRWQLENA-N
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GLP-1 receptor agonist 1 Usage And Synthesis

Description

Orforglipron (LY3502970) (GLP-1 receptor agonist 1) is  GLP-1 receptor agonist extracted from patent WO2018056453A1, Compound 67.

Uses

Glucagon-like peptide-1 (GLP-1) agonists (also known as GLP-1 receptor agonists, incretin mimetics, or GLP-1 analogs) represent a class of medications used to treat type 2 diabetes mellitus and, in some cases, obesity.

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