JNK INHIBITOR II, NEGATIVE CONTROL
JNK INHIBITOR II, NEGATIVE CONTROL Basic information
- Product Name:
- JNK INHIBITOR II, NEGATIVE CONTROL
- Synonyms:
-
- JNK INHIBITOR II, NEGATIVE CONTROL
- SAPK INHIBITOR II
- N1-METHYL-1,9-PYRAZOLOANTHRONE
- N'-METHYL-1,9-PYRAZOLOANTHRONE
- SP 600125, negative control
- JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem
- Dibenz[cd,g]indazol-6(2H)-one, 2-methyl-
- 2-Methyldibenzo[cd,g]indazol-6(2H)-one
- CAS:
- 54642-23-8
- MF:
- C15H10N2O
- MW:
- 234.25
- Mol File:
- Mol File
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JNK INHIBITOR II, NEGATIVE CONTROL Chemical Properties
- storage temp.
- -20C
- solubility
- DMSO: 10 mg/ml
- form
- Yellow solid
- color
- Yellow to orange
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JNK INHIBITOR II, NEGATIVE CONTROL Usage And Synthesis
Uses
JNK inhibitor II, negative control is the methylated analog of JNK inhibitor II and exhibits a lower affinity for JNK2 and JNK3. This compound is suitable to be used as a negative control in various kinase assays.
General Description
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 μM and 24 μM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
Biochem/physiol Actions
Target IC50: 18 μM and 24 μM against JNK2 and JNK3, respectively
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