11a-Hydroxy-16,17a-epoxyprogesterone
11a-Hydroxy-16,17a-epoxyprogesterone Basic information
- Product Name:
- 11a-Hydroxy-16,17a-epoxyprogesterone
- Synonyms:
-
- 11A-HYDROXY EPOXY PROGESTERONE
- 11A-HYDROXY 16,17A-EPOXY PROGESTERONE
- 16a,17-epoxy-11a-hydroxypregn-4-ene-3,20-dione
- 16A,17A-EPOXY-11A-HYDROXY-4-PREGNEN-3,20-DIONE
- 16alpha,17-epoxy-11alpha-hydroxypregn-4-ene-3,20-dione
- 16a,17-Epoxy-11a-hydroxypregn-4-ene
- 11alpha-Hydroxy-16alpha,17alpha Epoxy Progesterone
- 11 alpha-hydroxy Epoxy progesterone
- CAS:
- 19427-36-2
- MF:
- C21H28O4
- MW:
- 344.44
- EINECS:
- 243-049-5
- Mol File:
- 19427-36-2.mol
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11a-Hydroxy-16,17a-epoxyprogesterone Chemical Properties
- Melting point:
- 238.0-238.5 °C(Solv: benzene (71-43-2); cyclohexane (110-82-7))
- Boiling point:
- 508.7±50.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 14.42±0.70(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 19427-36-2(CAS DataBase Reference)
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11a-Hydroxy-16,17a-epoxyprogesterone Usage And Synthesis
Synthesis
11a-Hydroxy-16,17a-epoxyprogesterone can be prepared from diosgenin through the steps of ring-opening, acetylation, oxidation, hydrolysis, elimination, epoxidation, and oxidation.
Chemical Properties
Off-White Solid
Uses
11α-Hydroxy-16,17α-epoxyprogesterone is a steroid hormone. an analog of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
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