7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties

Melting point:

86 °C

Boiling point:

455.6±45.0 °C(Predicted)

Density 

1.204

Flash point:

229.3℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

2.83±0.20(Predicted)

color 

Light yellow to Amber to Dark green

InChI

InChI=1S/C16H19NO4/c1-4-17(5-2)12-8-7-11-9-13(15(18)20-6-3)16(19)21-14(11)10-12/h7-10H,4-6H2,1-3H3

InChIKey

MSOLGAJLRIINNF-UHFFFAOYSA-N

SMILES

C1(=O)OC2=CC(N(CC)CC)=CC=C2C=C1C(OCC)=O

EPA Substance Registry System

2H-1-Benzopyran-3-carboxylic acid, 7-(diethylamino)-2-oxo-, ethyl ester (28705-46-6)

Safety Information

HS Code 

29322090

7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC ACID ETHYL ESTER Usage And Synthesis

Uses

Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1].

References

[1] Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46(10):4846-52. DOI:10.1016/j.ejmech.2011.07.017

7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC ACID ETHYL ESTER(28705-46-6)Related Product Information

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