SB 221284
SB 221284 Basic information
- Product Name:
- SB 221284
- Synonyms:
-
- 5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE
- 2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
- SB 221284
- 1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
- CAS:
- 196965-14-7
- MF:
- C16H14F3N3OS
- MW:
- 353.36
- Mol File:
- 196965-14-7.mol
More
Less
SB 221284 Chemical Properties
- Melting point:
- 262-264 °C
- Boiling point:
- 536.2±50.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- DMSO: ~14 mg/mL, soluble
- pka
- 13.13±0.20(Predicted)
- form
- solid
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
More
Less
SB 221284 Usage And Synthesis
Uses
SB 221284 is a potent, selective SR-2C/SR-2B antagonist.
Definition
ChEBI: SB 221284 is an indolyl carboxylic acid.
Biological Activity
Potent, selective 5-HT 2C/2B receptor antagonist. pK i values are 6.4, 7.9 and 8.6 for 5-HT 2A , 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo .
SB 221284Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
BOC Sciences
- Tel
- info@bocsci.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing1@energy-chemical.com