3-MATIDA
3-MATIDA Basic information
- Product Name:
- 3-MATIDA
- Synonyms:
-
- 3-MATIDA
- ALPHA-AMINO-5-CARBOXY-3-METHYL-2-THIOPHENEACETIC ACID
- α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid
- 5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid
- 2-Thiopheneacetic acid, α-amino-5-carboxy-3-methyl-
- 3 MATIDA,3MATIDA
- CAS:
- 518357-51-2
- MF:
- C8H9NO4S
- MW:
- 215.23
- Product Categories:
-
- Glutamate receptor
- Mol File:
- 518357-51-2.mol
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3-MATIDA Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- Soluble to 100 mM in 1eq. NaOH and to 50 mM in DMSO
- form
- Powder
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3-MATIDA Usage And Synthesis
Uses
3-MATIDA is a potent mGluR-1 antagonist.
Definition
ChEBI: 5-[amino(carboxy)methyl]-4-methyl-2-thiophenecarboxylic acid is an alpha-amino acid.
Biological Activity
Potent metabotropic glutamate mGlu 1 receptor antagonist (IC 50 = 6.3 μ M at rat mGlu 1a ). Displays ≥ 40-fold selectivity over other receptors: mGlu 5 , mGlu 2 , mGlu 4a (IC 50 > 300 μ M), NMDA and AMPA (IC 50 = 250 μ M). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro . Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo .
3-MATIDASupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EnliPharma Technology Co., Ltd
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Aikon International Limited
- Tel
- 025-66113011 13155353615
- qzhang@aikonchem.com
Nextpeptide Inc
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com