H-ARG-GLY-GLU-SER-OH
H-ARG-GLY-GLU-SER-OH Basic information
- Product Name:
- H-ARG-GLY-GLU-SER-OH
- Synonyms:
-
- R-G-E-S
- rgespeptide
- ARG-GLY-GLU-SER
- H-ARG-GLY-GLU-SER-OH
- RGES; R-G-E-S
- [Glu3]-RGES,ControlforRGDPeptides
- (4S)-4-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid
- L-Serine, L-arginylglycyl-L-α-glutamyl-
- CAS:
- 93674-97-6
- MF:
- C16H29N7O8
- MW:
- 447.45
- Product Categories:
-
- Peptide
- Mol File:
- 93674-97-6.mol
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H-ARG-GLY-GLU-SER-OH Chemical Properties
- Density
- 1.61±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 2.95±0.10(Predicted)
- Sequence
- H-Arg-Gly-Glu-Ser-OH
MSDS
- Language:English Provider:SigmaAldrich
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H-ARG-GLY-GLU-SER-OH Usage And Synthesis
Uses
Arg-Gly-Glu-Ser is a polypeptide related to RGD and is a negative control for Arg-Gly-Asp-Ser (HY-12290)[1].
in vivo
Arg-Gly-Glu-Ser (5 mg/kg) in combination with LPS or saline + RGDS does not affect neutrophil and macrophage cell numbers and has no effect on protein accumulation compared with LPS- or saline-treated mice, respectively[1].
References
[1] Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. DOI:10.1186/1465-9921-10-18
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