Basic information Safety Supplier Related

TEMOCILLIN

Basic information Safety Supplier Related

TEMOCILLIN Basic information

Product Name:
TEMOCILLIN
Synonyms:
  • disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • (6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt
  • Temocillindisodiumsalt
  • (2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)aMino)-6-Methoxy-3,3-diMethyl-7-oxo-, disodiuM salt, (2S,5R,6S)-
  • BRL 17421 disodium
  • emocillindisodium
CAS:
61545-06-0
MF:
C16H18N2O7S2
MW:
414.45
EINECS:
262-835-9
Mol File:
61545-06-0.mol
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TEMOCILLIN Chemical Properties

storage temp. 
-20°C, stored under nitrogen
form 
Solid
color 
Off-white to yellow
Water Solubility 
Water : 250 mg/mL (545.35 mM; Need ultrasonic)
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TEMOCILLIN Usage And Synthesis

Uses

Temocillin Disodium is the salt of Temocillin, which is a β-lactam stable against most β-lactamases is used as an alternative to carbapenems.

Definition

ChEBI: Temocillin disodium is an organic sodium salt. It contains a temocillin(2-).

Biological Activity

Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.

TEMOCILLINSupplier

NCE Biomedical Co.,Ltd.
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4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Beijing Universal Century Technology Co., Ltd.
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400-8706899
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hysj_bj.com
3B Scientific (Wuhan) Corporation Limited
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0086-27-88063677 18186135292
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sales@3bsc.com
Credit Asia Chemical Co., Ltd.
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+86 (21) 61124340
Chizhou Kailong Import and Export Trade Co., Ltd.
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xg01_gj@163.com