TEMOCILLIN
TEMOCILLIN Basic information
- Product Name:
- TEMOCILLIN
- Synonyms:
-
- disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- (6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt
- Temocillindisodiumsalt
- (2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)aMino)-6-Methoxy-3,3-diMethyl-7-oxo-, disodiuM salt, (2S,5R,6S)-
- BRL 17421 disodium
- emocillindisodium
- CAS:
- 61545-06-0
- MF:
- C16H18N2O7S2
- MW:
- 414.45
- EINECS:
- 262-835-9
- Mol File:
- 61545-06-0.mol
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TEMOCILLIN Chemical Properties
- storage temp.
- -20°C, stored under nitrogen
- form
- Solid
- color
- Off-white to yellow
- Water Solubility
- Water : 250 mg/mL (545.35 mM; Need ultrasonic)
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TEMOCILLIN Usage And Synthesis
Uses
Temocillin Disodium is the salt of Temocillin, which is a β-lactam stable against most β-lactamases is used as an alternative to carbapenems.
Definition
ChEBI: Temocillin disodium is an organic sodium salt. It contains a temocillin(2-).
Biological Activity
Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.
TEMOCILLINSupplier
NCE Biomedical Co.,Ltd.
- Tel
- 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Beijing Universal Century Technology Co., Ltd.
- Tel
- 400-8706899
- hysj_bj.com
3B Scientific (Wuhan) Corporation Limited
- Tel
- 0086-27-88063677 18186135292
- sales@3bsc.com
Credit Asia Chemical Co., Ltd.
- Tel
- +86 (21) 61124340
Chizhou Kailong Import and Export Trade Co., Ltd.
- Tel
- xg01_gj@163.com