800CW acid (IRDye 800CW acid equivalent) Chemical Properties

form 

Solid

color 

Green to dark green

800CW acid (IRDye 800CW acid equivalent) Usage And Synthesis

Description

800CW acid (IRDye??800CW acid equivalent) is a near-infrared high water-soluble fluorescent dye with excitation/emission maximum 780/800 nm. The dye has four water soluble SO3Na groups which make it more water soluble and less aggregation in bio application. The dye and its probes have enhanced sensitivity (higher signal-to-noise ratios) because media or tissues have very low background autofluorescence in the near-infrared region. 800CW dye-conjugated agents and probes are currently propelling more than a dozen Phase I or Phase II clinical trials, more than any other near-infrared fluorescent dye on the market. More than 4000 papers are cited in 800CW application worldwide. IRDye?? a registered trademark of LI-COR.

Uses

800CW acid is a near-infrared (NIR) dye that can be used for protein labeling. 800CW acid can be used for in vivo imaging studies[1].

References

[1] Li Y, et al. Monitoring Tumor Targeting and Treatment Effects of IRDye 800CW and GX1-Conjugated Polylactic Acid Nanoparticles Encapsulating Endostar on Glioma by Optical Molecular Imaging. Mol Imaging. 2015;14:356-65. PMID:26162457

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