S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Chemical Properties

Melting point:

74-76°C

Boiling point:

290.1±30.0 °C(Predicted)

Density 

1.111±0.06 g/cm3(Predicted)

storage temp. 

Room Temperature, under inert atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

14.35±0.20(Predicted)

color 

White to Off-White

CAS DataBase Reference

116817-84-6(CAS DataBase Reference)

S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

rac-α-[2-(Dimethylamino)ethyl]-3-thiophenemethanol is an intermediate in the synthesis of rac Duloxetine 3-Thiophene Isomer (D721025). rac Duloxetine 3-Thiophene Isomer Hydrochloride is an isomeric impurity of the antidepressant Duloxetine Hydrochloride (D721000).

Uses

S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide is a useful synthetic intermediate.

S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide(116817-84-6)Related Product Information

• (S)-Duloxetine SuccinaMide
• Duloxetine IMpurity A
• S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide
• S-(+)-N,N-DIMETHYL-3-(1-NAPHTHLENYLOXY)-3-(2-THIENYL)-PROPANAMINE
• 3-THIOPHENEPROPANAMINE, N,N-DIMETHYL-GAMMA-(1-NAPHTHALENYLOXY)-, ETHANEDIOATE(1:1)
• (R)-(+)- N,N-dimethyl-3-hydroxy-3-(2-thienyl)propanamine
• (RS)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)PROPANAMINE
• 4-HYDROXY-4-(2-THIENYL)-1-ISOPROPYLPIPERIDINE
• 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-METHYLPIPERIDINE
• AKOS 91503
• 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-METHYLPIPERIDINE
• 1-(2,5-DICHLORO-3-THIENYL)-3-(DIMETHYLAMINO)-1-PROPANOL
• AKOS 91648
• AKOS 94341
• 4-HYDROXY-4-(2-THIENYL)-1-METHYLPIPERIDINE
• 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-ISOPROPYLPIPERIDINE
• AKOS 91515
• 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-ISOPROPYLPIPERIDINE