3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol
3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol Basic information
- Product Name:
- 3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol
- Synonyms:
-
- 3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol
- CAS:
- 2378150-09-3
- MF:
- C23H44O11
- MW:
- 496.59
- Mol File:
- 2378150-09-3.mol
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3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol Chemical Properties
- Boiling point:
- 550.9±45.0 °C(Predicted)
- Density
- 1.096±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
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3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-ol Usage And Synthesis
Uses
Propargyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG10-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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