rociverine
rociverine Basic information
- Product Name:
- rociverine
- Synonyms:
-
- rociverine
- Rociverine (base and/or unspecified salts)
- 1-Hydroxy-[1,1'-bi(cyclohexane)]-2-carboxylic acid 2-(diethylamino)-1-methylethyl ester
- [1,1'-Bicyclohexyl]-2-carboxylic acid, 1-hydroxy-, 2-(diethylamino)-1-methylethyl ester, (1R,2R)-rel-
- Rociverinum
- CAS:
- 53716-44-2
- MF:
- C20H37NO3
- MW:
- 339.51
- EINECS:
- 2587119
- Mol File:
- 53716-44-2.mol
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rociverine Chemical Properties
- Boiling point:
- bp0.1 148-150°
- refractive index
- nD20 1.4820
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rociverine Usage And Synthesis
Uses
Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity[1].
References
[1] Stereoselective inhibition of muscarinic receptor subtypes by the eight stereoisomers related to rociverine
rociverineSupplier
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