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(2R)-2-Azido-6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]hexanoic acid

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(2R)-2-Azido-6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]hexanoic acid Basic information

Product Name:
(2R)-2-Azido-6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]hexanoic acid
Synonyms:
  • N3-D-Lys(Fmoc)-OH
  • (2R)-2-azido-6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
  • (R)-2-Azido-6-(Fmoc-amino)hexanoic acid
CAS:
1994300-35-4
MF:
C21H22N4O4
MW:
394.42
Mol File:
1994300-35-4.mol
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(2R)-2-Azido-6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]hexanoic acid Usage And Synthesis

Uses

N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments[1]. N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Zhang X, et al. Applications of azide-based bioorthogonal click chemistry in glycobiology. Molecules. 2013 Jun 19;18(6):7145-59. DOI:10.3390/molecules18067145

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