eritrityl tetranitrate Chemical Properties

Melting point:

61°

Boiling point:

443.16°C (rough estimate)

Density 

1.757±0.06 g/cm3(Predicted)

refractive index 

1.8500 (estimate)

eritrityl tetranitrate Usage And Synthesis

Chemical Properties

Crystals. Soluble in alcohol, ether, and glycerol; insoluble in water.

Uses

Vasodilator (coronary). Cardilate (Glaxo Wellcome{) [Name previously used: Erythrol Tetranitrate.].

Definition

ChEBI: Erythritol in which each of the hydroxy groups has been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to nitroglycerin. It is usually used diluted with lactose or other suitable inert excipients, in order to mini ise the risk of explosion; undiluted erythrityl tetranitrate can be exploded by percussion or excessive heat.

Hazard

Severe explosion risk when shocked or heated.

Purification Methods

Crystallise cordite from EtOH. It explodes on percussion at ~220-460o and is a vasodilator. [Beilstein 1 III 2358, 1 IV 2809.]

eritrityl tetranitrate(7297-25-8)Related Product Information

• Alginic Sodium Diester
• Erythritol
• SODIUM TREHALOSE SULFATE
• 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE