(1R,2R)-1,2-BIS(2-HYDROXYPHENYL)ETHYLENEDIAMINE, 95% Chemical Properties

Melting point:

157-163 °C

Boiling point:

457.9±40.0 °C(Predicted)

Density 

1.294±0.06 g/cm3(Predicted)

pka

9.15±0.35(Predicted)

form 

Powder

color 

white to off-white

optical activity

[α]22/D +62°, c = 1% in chloroform

Sensitive 

air sensitive

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

HS Code 

2922.19.7000

(1R,2R)-1,2-BIS(2-HYDROXYPHENYL)ETHYLENEDIAMINE, 95% Usage And Synthesis

Uses

2,2''-[(1R,2R)-1,2-Diamino-1,2-ethanediyl]bisphenol is a useful synthetic compound.

Uses

(1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine can be used as a precursor for the synthesis of:

• Enantiomerically pure trans-3-arylpiperazine-2-carboxylic acid derivatives via diaza-Cope rearrangement (DCR).
• 4,4′-(1,2-Diazaniumylethane-1,2-diyl)dibenzoate trihydrate by treating with terephthalaldehydic acid.

General Description

(1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine or (R, R)-1,2-bis(2-hydroxyphenyl)-1,2-diaminoethane (HPEN) is commonly used in the stereoselective synthesis of enantiopure compounds.

(1R,2R)-1,2-BIS(2-HYDROXYPHENYL)ETHYLENEDIAMINE, 95%(870991-70-1)Related Product Information

• AURORA KA-6898
• Phenol, 3,3'-(1,2-diamino-1,2-ethanediyl)bis-, [S-(S*,S*)]- (9CI)
• Phenol, 4,4'-[(1S,2S)-1,2-diamino-1,2-ethanediyl]bis- (9CI)
• Phenol, 3,3'-(1,2-diamino-1,2-ethanediyl)bis-, [R-(R*,R*)]- (9CI)
• Phenol,3-[1-(methylamino)ethyl]-
• (1S,2S)-1,2-Bis(2-hydroxyphenyl)ethylenediaMine
• Phenol, 3,3'-(1,2-diamino-1,2-ethanediyl)bis-, [R-(R*,R*)]- (9CI) hydrochloride
• Phenol, 4,4'-(1,2-diamino-1,2-ethanediyl)bis- (9CI)
• Phenol, 4,4'-[(1R,2R)-1,2-diamino-1,2-ethanediyl]bis- (9CI)
• (1R,2R)-(-)-1,2-Bis(4-hydroxyphenyl)ethylenediaminedihydrochloride
• Phenol, 4,4'-[(1S,2S)-1,2-diamino-1,2-ethanediyl]bis- (9CI) hydrochloride
• (R,R)-1,2-Bis(2,4,6-trimethoxyphenyl)-1,2-ethanediamine dihydrochloride
• (1R,2R)-1,2-BIS(2-HYDROXYPHENYL)ETHYLENEDIAMINE, 95%