2-METHYLSEROTONIN MALEATE SALT
2-METHYLSEROTONIN MALEATE SALT Basic information
- Product Name:
- 2-METHYLSEROTONIN MALEATE SALT
- Synonyms:
-
- 2-METHYLSEROTONIN MALEATE SALT
- 2-methyl-5-hydroxytryptamine maleate salt
- 2-Methyl-5-hydroxytryptamine maleate salt, 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
- 2-Me-5-HT maleate
- 2-Methyl-5-HT maleate
- 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
- 2-Me-HT maleate
- 2Methyl5HT maleate,2 Methyl 5 HT maleate
- CAS:
- 78263-91-9
- MF:
- C15H18N2O5
- MW:
- 306.31382
- Mol File:
- 78263-91-9.mol
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2-METHYLSEROTONIN MALEATE SALT Chemical Properties
- Melting point:
- 186-187 °C
- storage temp.
- −20°C
- solubility
- H2O: soluble5mg/mL, clear
- form
- powder
- color
- white to brown
- Water Solubility
- H2O: 5mg/mL, clear
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2-METHYLSEROTONIN MALEATE SALT Usage And Synthesis
Uses
2-Methylserotonin Maleate Salt is a 5-HT3 serotonin receptor agonist.
Biological Activity
2-Methylserotonin is a selective full agonist at the 5-HT3 receptor.', '2-Methylserotonin maleate, a serotonin type 3 (5-HT3) agonist is used as a training drug in drug discrimination studies. Use of 2-methylserotonin in evolving rats shows to reflect the ontogeny of the spinal 5-HT3 receptor system.
in vivo
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1].
| Animal Model: | Male Sprague-Dawley rats[1] |
| Dosage: | 3 mg/kg |
| Administration: | I.p.; 45 minutes |
| Result: | Significantly decreased time of immobility thus showing anti-depressive-like effects. |
IC 50
5-HT3 Receptor
2-METHYLSEROTONIN MALEATE SALTSupplier
Jinan Yaoyan Pharmaceutical Co., Ltd.
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- jnyaoyan@163.com
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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- meitaochem@126.com
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TargetMol Chemicals Inc.
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- +1-781-999-5354; +17819995354
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Energy Chemical
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