Basic information Safety Supplier Related

Zolasartan

Basic information Safety Supplier Related

Zolasartan Basic information

Product Name:
Zolasartan
Synonyms:
  • 3-[[3-bromo-2-[2-(2H-tetrazol-5-yl)phenyl]-1-benzofuran-5-yl]methyl]-2-butyl-5-chloroimidazole-4-carboxylic acid
  • Zolasartan
  • GR 117289
  • 1H-Imidazole-5-carboxylic acid, 1-[[3-bromo-2-[2-(2H-tetrazol-5-yl)phenyl]-5-benzofuranyl]methyl]-2-butyl-4-chloro-
  • GR 117289C
  • GR-117289C
CAS:
145781-32-4
MF:
C24H20BrClN6O3
MW:
555.818
Mol File:
145781-32-4.mol
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Zolasartan Chemical Properties

Boiling point:
773.3±70.0 °C(Predicted)
Density 
1.67±0.1 g/cm3(Predicted)
pka
0.74±0.50(Predicted)
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Zolasartan Usage And Synthesis

Definition

ChEBI: Zolasartan is a member of the class of 1-benzofurans that is 3-bromo-1-benzofuran which is substituted by a 2-(1H-tetrazol-5-yl)phenyl group at position 2 and by a (2-butyl-5-carboxy-4-chloro-1H-imidazol-1-yl)methyl group at position 5. It is an angiotensin II receptor type 1 (AT1) antagonist and was in clinical trials for the treatment of hypertension (now discontinued). It has a role as an angiotensin receptor antagonist and an antihypertensive agent. It is a member of tetrazoles, an imidazolyl carboxylic acid, a member of 1-benzofurans, an organochlorine compound, an organobromine compound, a monocarboxylic acid and a biaryl. It is a conjugate acid of a zolasartan(2-).

ZolasartanSupplier

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