Utibaprilat
Utibaprilat Basic information
- Product Name:
- Utibaprilat
- Synonyms:
-
- Utibaprilat
- (2S)-5-tert-Butyl-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-2,3-dihydro-1,3,4-thiadiazole-2β-carboxylic acid
- FPL-63674
- Utibaprirat
- CAS:
- 109683-79-6
- MF:
- C20H27N3O5S
- MW:
- 421.515
- Mol File:
- 109683-79-6.mol
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Utibaprilat Usage And Synthesis
Uses
Utibaprilat (FPL 63674XX) is a ACE inhibitor that is a major degradation product of Utibapril (HY-101681)[1].
References
[1] Krier M, et al. Bioisosteric similarity of molecules based on structural alignment and observed chemical replacements in drugs. J Chem Inf Model. 2009 May;49(5):1280-97. DOI:10.1021/ci8003418
[2] Jagota N K, et al. HPLC Determination of Utibapril and its Diacid FPL 63674XX in Rodent Laboratory Diet Using Selective Extraction and Gradient Elution Chromatography. Journal of liquid chromatography, 1991, 14(15): 2979-2991.