Basic information Safety Supplier Related

1-(Methylnitrosoamino)-2-propanol

Basic information Safety Supplier Related

1-(Methylnitrosoamino)-2-propanol Basic information

Product Name:
1-(Methylnitrosoamino)-2-propanol
Synonyms:
  • MHP
  • 1-(Methylnitrosoamino)-2-propanol
  • (S)-methyl 2-hexanamido-3-(4-hydroxyphenyl)propanoate
  • Defensamide
  • Defensamide(MHP)
  • Methyl caprooyl tyrosinate
  • L-Tyrosine, N-(1-oxohexyl)-, methyl ester
  • methyl 2-hexanamido-3-(4-hydroxyphenyl)propanoate
CAS:
1104874-94-3
MF:
C16H23NO4
MW:
293.36
Mol File:
1104874-94-3.mol
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1-(Methylnitrosoamino)-2-propanol Chemical Properties

Boiling point:
490.9±35.0 °C(Predicted)
Density 
1.117±0.06 g/cm3(Predicted)
solubility 
DMSO:100.0(Max Conc. mg/mL);340.88(Max Conc. mM)
H2O:50.0(Max Conc. mg/mL);170.44(Max Conc. mM)
pka
9.76±0.15(Predicted)
form 
Solid
color 
White to off-white
Cosmetics Ingredients Functions
SKIN PROTECTING
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1-(Methylnitrosoamino)-2-propanol Usage And Synthesis

Uses

MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity[1].

IC 50

SphK1

References

[1] Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34. DOI:10.1016/j.jdermsci.2015.06.007

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