Trebenzomine
Trebenzomine Basic information
- Product Name:
- Trebenzomine
- Synonyms:
-
- Trebenzomine
- 3,4-Dihydro-3-(dimethylamino)-2-methyl-2H-1-benzopyran
- N,N,2-Trimethyl-3-chromanamine
- 2H-1-Benzopyran-3-amine, 3,4-dihydro-N,N,2-trimethyl-
- CAS:
- 23915-73-3
- MF:
- C12H17NO
- MW:
- 191.27
- Mol File:
- 23915-73-3.mol
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Trebenzomine Chemical Properties
- Boiling point:
- 276.7±29.0 °C(Predicted)
- Density
- 1.04±0.1 g/cm3(Predicted)
- pka
- 8.82±0.40(Predicted)
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Trebenzomine Usage And Synthesis
Uses
Trebenzomine (CI-686 free base) is a centrally acting psychotropic compound. Trebenzomine has both neuroleptic and stimulant activity. Trebenzomine potentiates Methamphetamine-induced self-stimulation. Trebenzomine reduces septal hyperirritability, suppression of conditioned avoidance behavior, blocks Apomorphine (HY-12723)-induced emesis in dogs[1].
References
[1] Georgotas A, et al. A double-blind comparison of trebenzomine and thioridazine in the treatment of schizophrenia. Psychopharmacology (Berl). 1981;73(3):292-4. DOI:10.1007/BF00422420
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