AH 21-132
AH 21-132 Basic information
- Product Name:
- AH 21-132
- Synonyms:
-
- AH 21-132
- Benzafentrine
- Benafentrine dimaleate
- CAS:
- 76166-55-7
- MF:
- C23H27N3O3.2C4H4O4
- MW:
- 625.628
- Mol File:
- 76166-55-7.mol
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AH 21-132 Usage And Synthesis
Description
Benafentrine dimaleate is a phosphodiesterase (PDE) 3/4 inhibitors and platelet activating factor receptor (PAFR) antagonists potentially for the treatment asthma.
Uses
Benafentrine maleate is a platelet activating factor receptor (PAFR) antagonist and a PDE 4 inhibitor[1].
References
[1] Kelly JJ, et al. Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors. Biochem J. 1996 Sep 1;318 ( Pt 2)(Pt 2):425-36. DOI:10.1042/bj3180425