SR 58611A
SR 58611A Basic information
- Product Name:
- SR 58611A
- Synonyms:
-
- SR 58611A hydrochloride
- Amibegron hydrochloride
- SR 58611A
- [[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]ox]yaceticacidethylesterhydrochloride
- Acetic acid, [[(7S)?-?7-?[[(2R)?-?2-?(3-?chlorophenyl)?-?2-?hydroxyethyl]?amino]?-?5,?6,?7,?8-?tetrahydro-?2-?naphthalenyl]?oxy]?-?, ethyl ester, hydrochloride (1:1)
- Amibegron HCl
- Amibegron hydrochloride（SR 58611A）
- CAS:
- 121524-09-2
- MF:
- C22H27Cl2NO4
- MW:
- 440.36
- Mol File:
- 121524-09-2.mol
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SR 58611A Chemical Properties
- storage temp.
- -20°C
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- color
- white to beige
- optical activity
- [α]/D -75 to -95°, c = 0.5 in methanol
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SR 58611A Usage And Synthesis
Uses
SR 58611A is a selective β3-adrenergic receptor agonist with anxiolytic and antidepressant properties (1,2). SR 58611A is blood brain barrier permeable.
Biochem/physiol Actions
SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC50 for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.
storage
Desiccate at RT
SR 58611ASupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Sigma-Aldrich
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- 021-61415566 800-8193336
- orderCN@merckgroup.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com