HNS 32
HNS 32 Basic information
- Product Name:
- HNS 32
- Synonyms:
-
- HNS 32
- 1-Azulenecarboximidamide, N,N,3,8-tetramethyl-5-(1-methylethyl)-N'-(2-pyridinylmethyl)-
- CAS:
- 186086-10-2
- MF:
- C24H29N3
- MW:
- 359.51
- Mol File:
- 186086-10-2.mol
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HNS 32 Chemical Properties
- Boiling point:
- 505.3±60.0 °C(Predicted)
- Density
- 1.03±0.1 g/cm3(Predicted)
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HNS 32 Usage And Synthesis
Uses
HNS-32 is a compound with antiarrhythmic and vasodilatory effects in canine hearts, showing superior protective effects against ischemic and reperfusion arrhythmias compared to an equivalent dose of Mexiletine hydrochloride (HY-A0093). Furthermore, HNS-32 exhibits significant negative chronotropic effects on mammalian ventricular myocardium, indicating its potential application value in the study of acute coronary syndrome[1].
References
[1] Saitoh, et al. "Effects of HNS-32, a novel antiarrhythmic drug, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats." Molecular and Cellular Biochemistry 205 (2000): 133-140. DOI:10.1023/a:1007074115503