CP 67015
CP 67015 Basic information
- Product Name:
- CP 67015
- Synonyms:
-
- CP 67015
- 1-Ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
- 1-ethyl-6,8-difluoro-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
- CCRIS 2955
- CP-67
- CP67015,CP 67015
- 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-
- CAS:
- 100325-51-7
- MF:
- C17H12F2N2O3
- MW:
- 330.29
- Mol File:
- 100325-51-7.mol
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CP 67015 Chemical Properties
- Boiling point:
- 496.7±45.0 °C(Predicted)
- Density
- 1.3683 (estimate)
- pka
- -0.37±0.20(Predicted)
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CP 67015 Usage And Synthesis
Uses
CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects[1].
in vivo
CP-67015 (a single dose 1000 mg/kg or 500 mg/kg/day for 5 days; i.p.) induces chromosome damage in male CD-1 mice in mouse bone marrow cells[1].
IC 50
Quinolone; Topoisomerase II
References
[1] Holden HE, et, al. Genetic profile of a nalidixic acid analog: a model for the mechanism of sister chromatid exchange induction. Environ Mol Mutagen. 1989;13(3):238-52. DOI:10.1002/em.2850130308
CP 67015Supplier
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