aplasmomycin
aplasmomycin Basic information
- Product Name:
- aplasmomycin
- Synonyms:
-
- aplasmomycin
- CAS:
- 61230-25-9
- MF:
- C40H60BNaO14
- MW:
- 798.71
- Mol File:
- 61230-25-9.mol
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aplasmomycin Chemical Properties
- Melting point:
- 283-285° (dec)
- alpha
- D22 +225° (c = 1.24 in chloroform)
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aplasmomycin Usage And Synthesis
Uses
Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo[1].
Definition
ChEBI: (+)-aplasmomycin is a macrolide antibiotic and a boron oxoanion.
References
[1] Shimizu Y, et al. Aplasmomycin and boromycin are specific inhibitors of the futalosine pathway. J Antibiot (Tokyo). 2018 Nov;71(11):968-970. DOI:10.1038/s41429-018-0087-2