N-METHYL-1,3-BENZOXAZOL-2-AMINE Chemical Properties

Melting point:

75-77°

Boiling point:

239.8±23.0 °C(Predicted)

Density 

1.244±0.06 g/cm3(Predicted)

pka

2.84±0.10(Predicted)

Safety Information

HazardClass 

IRRITANT

N-METHYL-1,3-BENZOXAZOL-2-AMINE Usage And Synthesis

Uses

N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism[1].

References

[1] Prangthip P, et al. Anthelmintic efficacy evaluation and mechanism of N-methylbenzo[d]oxazol-2-amine. Sci Rep. 2023;13(1):22840. Published 2023 Dec 21. DOI:10.1038/s41598-023-50305-y

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