1-BOC-4-(PIPERIDIN-4-YL)-PIPERAZINE Chemical Properties

Melting point:

70-74°C

Boiling point:

362.9±42.0 °C(Predicted)

Density 

1.069

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

powder

pka

10.27±0.10(Predicted)

Appearance

White to off-white Solid

InChI

InChI=1S/C14H27N3O2/c1-14(2,3)19-13(18)17-10-8-16(9-11-17)12-4-6-15-7-5-12/h12,15H,4-11H2,1-3H3

InChIKey

IMFPSYLOYADSFR-UHFFFAOYSA-N

SMILES

N1(C(OC(C)(C)C)=O)CCN(C2CCNCC2)CC1

Safety Information

WGK Germany 

WGK 3

HS Code 

2933599590

Storage Class

11 - Combustible Solids

1-BOC-4-(PIPERIDIN-4-YL)-PIPERAZINE Usage And Synthesis

Uses

1-Boc-4-(piperidin-4-yl)-piperazine is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.

Uses

A semi-flexible linker useful for PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of PROTACs may impact degradation kinetics as well as ADMET properties of PROTACs.
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