5,7-Bis(acetyloxy)-2-[4-(acetyloxy)-3-methoxyphenyl]-3,6-dimethoxy-4H-1-benzopyran-4-one Chemical Properties

Boiling point:

599.9±50.0 °C(Predicted)

Density 

1.40±0.1 g/cm3(Predicted)

5,7-Bis(acetyloxy)-2-[4-(acetyloxy)-3-methoxyphenyl]-3,6-dimethoxy-4H-1-benzopyran-4-one Usage And Synthesis

Uses

Jaceidin triacetate(compound 54) is a natural compound isolated formmarulabark.Jaceidin triacetatecan inhibitSARS-CoV-2 Mpro, with theIC50of 11.9μM.Jaceidin triacetateinhibits the replication of Sars-Cov-2 Viral in Vero-E6 cells[1][2].

References

[1] Cádiz-Gurrea ML, et al. Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches. Molecules. 2019;24(5):966. DOI:10.3390/molecules24050966
[2] Moua Yang, et al. Inhibition of Sars-Cov-2 Viral Replication and In Vivo Thrombus Formation By a Novel Plant Flavonoid. Blood. Volume 138, Supplement 1, 23 November 2021, Page 3144