Basic information Safety Supplier Related

3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE

Basic information Safety Supplier Related

3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE Basic information

Product Name:
3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE
Synonyms:
  • 3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE
  • CAY10550
  • 2,4-Dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one
  • TCS PrP Inhibitor 13
  • 3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-5(4H)-one
  • 5-(4-nitrophenyl)-2-phenyl-4H-pyrazol-3-one
  • 3H-Pyrazol-3-one, 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-
  • Inhibitor,inhibit,cellular,ScN2a,agent,Apoptosis,antiprion,protease-resistant,TCS PrP Inhibitor13,prion,TCS PrP Inhibitor-13,TCS PrP Inhibitor 13
CAS:
34320-83-7
MF:
C15H11N3O3
MW:
281.27
Mol File:
34320-83-7.mol
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3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE Chemical Properties

storage temp. 
Store at +4°C
solubility 
Soluble to 100 mM in DMSO and to 25 mM in ethanol
form 
Powder
color 
White to yellow
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3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONE Usage And Synthesis

Uses

TCS PrP Inhibitor 13 is a PrP-res accumulation inhibitor.

Biological Activity

Antiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC 50 = 3 nM).

3-(4-NITROPHENYL)-1-PHENYL-2-PYRAZOLIN-5-ONESupplier

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