(+)-3R,5S-FLUVASTATIN SODIUM SALT
(+)-3R,5S-FLUVASTATIN SODIUM SALT Basic information
- Product Name:
- (+)-3R,5S-FLUVASTATIN SODIUM SALT
- Synonyms:
-
- (+)-3R,5S-FLUVASTATIN SODIUM SALT
- (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid
- (+)-3R,5S-Fluvastatin-d6 sodiuM salt
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, (3R,5S,6E)-
- 5S)-XU 62-320 free acid
- CAS:
- 155229-75-7
- MF:
- C24H26FNO4
- MW:
- 411.47
- Mol File:
- 155229-75-7.mol
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(+)-3R,5S-FLUVASTATIN SODIUM SALT Chemical Properties
- Melting point:
- >150°C (dec.)
- Boiling point:
- 681.8±55.0 °C(Predicted)
- Density
- 1.23
- storage temp.
- -20°C Freezer
- solubility
- DMSO, Methanol, Water
- pka
- 4.27±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow
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(+)-3R,5S-FLUVASTATIN SODIUM SALT Usage And Synthesis
Uses
A synthetic HMG-CoA reductase inhibitor. Antilipemic.This compound contains residual sodium chloride which is quantified on the certificate of analysis.
Definition
ChEBI: (3R,5S)-fluvastatin is a (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid diastereoisomer in which the stereocentres beta- and delta- to the carboxy group have R and S configuration, respectively. The drug fluvastatin is an equimolar mixture of this compound and its enantiomer. It is a (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid and a statin (synthetic). It is a conjugate acid of a (3R,5S)-fluvastatin(1-). It is an enantiomer of a (3S,5R)-fluvastatin.
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