Basic information Safety Supplier Related

N-Deboc-Docetaxel

Basic information Safety Supplier Related

N-Deboc-Docetaxel Basic information

Product Name:
N-Deboc-Docetaxel
Synonyms:
  • N-Deboc-Docetaxel
  • N-DesBoc Docetaxel
  • 10-Desacetyl-N-debenzoylpaclitaxel
  • N-De(tert-butoxycarbonyl)-10-deacetyldocetaxel
  • N-Debenzoyl-10-deacetylpaclitaxel
  • Docetaxel impurity 3/N-DesBoc Docetaxel/10-Desacetyl-N-debenzoylpaclitaxel/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12
  • Docetaxel Impurity 40
  • Benzenepropanoic acid, β-amino-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
CAS:
133524-69-3
MF:
C38H45NO12
MW:
707.76
Mol File:
133524-69-3.mol
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N-Deboc-Docetaxel Chemical Properties

Melting point:
>150°C (dec.)
Boiling point:
846.0±65.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.19±0.45(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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N-Deboc-Docetaxel Usage And Synthesis

Uses

N-DesBoc Docetaxel is an impurity in the synthesis of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.

N-Deboc-DocetaxelSupplier

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