H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH
H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH Basic information
- Product Name:
- H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH
- Synonyms:
-
- H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH
- TLQP-21 (huMan)
- L-Arginine, L-threonyl-L-leucyl-L-glutaminyl-L-prolyl-L-prolyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-histidyl-L-tyrosyl-L-histidyl-L-histidyl-L-alanyl-L-leucyl-L-prolyl-L-prolyl-L-seryl-
- CAS:
- 1259837-37-0
- MF:
- C110H176N40O27
- MW:
- 2490.83
- Mol File:
- 1259837-37-0.mol
H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH Chemical Properties
- storage temp.
- -20°C
- form
- lyophilized powder
- color
- white
- Water Solubility
- deionized water: soluble
- Sequence
- Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg
H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH Usage And Synthesis
Uses
TLQP-21 (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
Biological Activity
TLQP-21 peptide is involved in the central and peripheral nervous system activities such as regulating reproductive and circadian behaviors, feeding, and body weight. It is also involved in regulating neuropathic pain and peripheral adiposity. TLQP-21 plays a role in stimulating the secretion of insulin and prevents apoptosis of pancreatic cells. It also activates the complement C3a receptor-1 (C3aR1) in the brain.
References
[1] Birnbaum S, et al. Peptide screening. Current Opinion in Biotechnology, 1992, 3(1): 49-54.
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