1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]- Chemical Properties

Boiling point:

616.8±55.0 °C(Predicted)

Density 

1.27±0.1 g/cm3 (20 ºC 760 Torr)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

14.84±0.10(Predicted)

color 

White to Pale Brown

1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]- Usage And Synthesis

Uses

An impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.

Uses

As an impurity in the synthesis of Silodosin (S465000),2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-1H-indole-7-carbonitrile is used in treatment of benign prostatic hypertophy.

1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-(885340-13-6)Related Product Information

• Silodosin Carboxylic Acid Impurity
• Silodosin
• 1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-1H-indole-7-carboxaMide
• NCFJJNFEEPMRAQ-XMMPIXPASA-N
• Silodosin Glucuronide
• 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile
• (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-1-(3-hydroxypropyl)indoline-7-carboxamide(WXG00186)
• Silodosin β-D-Glucuronide Sodium Salt
• Silodosin
• 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
• O-Acetyl Silodosin
• 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile
• Silodosin Impurity 18
• Silodosin β-D-Glucuronide N-Carboxybenzyl O-Methyl Tri-acetate
• Silodosin Impurity 26
• Silodosin-d6
• Silodosin Impurity 33
• S-Silodosin