Basic information Safety Supplier Related

5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE

Basic information Safety Supplier Related

5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE Basic information

Product Name:
5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE
Synonyms:
  • BUTTPARK 82\04-73
  • AKOS BBS-00001394
  • 5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE
  • 5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2-THIOL
  • 5,7-DIMETHYL-2-MERCAPTO-1,2,4-TRIAZOLO(1,5-A)PYRIMIDINE
  • [1,2,4]Triazolo[1,5-a]pyrimidine-2(1H)-thione, 5,7-dimethyl-
  • 5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2(1H)-thione
  • KKJ 00626
CAS:
51646-17-4
MF:
C7H8N4S
MW:
180.23
Mol File:
51646-17-4.mol
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5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE Chemical Properties

Melting point:
256°
Boiling point:
256°C
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Safety Information

HazardClass 
IRRITANT
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5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDE Usage And Synthesis

Uses

KKJ00626 is an inhibitor for Hepatitis B virus (HBV) with an IC50 of 0.12~0.23 μM. KKJ00626 inhibits the interaction between HBV core protein and the surface protein PreS region, prevents the maturation and secretion of HBV particles, and exhibits antiviral efficacy[1].

References

[1] Asif-Ullah M, et al., Identification of compounds that inhibit the interaction between core and surface protein of hepatitis B virus. Antiviral Res. 2006 Jun;70(2):85-90. DOI:10.1016/j.antiviral.2006.01.003

5,7-DIMETHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLHYDROSULFIDESupplier

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