28-O-Methyl-rapaMycin Chemical Properties

Melting point:

>102°C (dec.)

Boiling point:

961.9±75.0 °C(Predicted)

Density 

1.16±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

10.40±0.70(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

28-O-Methyl-rapaMycin Usage And Synthesis

Uses

28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.

28-O-Methyl-rapaMycin(159351-88-9)Related Product Information

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