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Ethyl 6-bromopicolinate

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Ethyl 6-bromopicolinate Basic information

Product Name:
Ethyl 6-bromopicolinate
Synonyms:
  • Ethyl 6-bromopicolinate, 2-Bromo-6-(ethoxycarbonyl)pyridine
  • ETHYL 6-BROMOPYRIDINE-2-CARBOXYLATE
  • ETHYL-6-BROMO-2-PYRIDINECARBOXYLATE
  • 6-BROMOPYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
  • 6-BROMOPYRIDINE-2-ETHYL CARBOXYLATE
  • RARECHEM AL BI 0899
  • Ethyl 6-bromo-2-piperidinecarboxylate
  • ETHYL 6-BROMOPICOLINATE
CAS:
21190-88-5
MF:
C8H8BrNO2
MW:
230.06
EINECS:
673-818-4
Product Categories:
  • blocks
  • Bromides
  • Pyridines
  • Pyridine
  • Pyridine Series
  • Heterocycle-Pyridine series
Mol File:
21190-88-5.mol
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Ethyl 6-bromopicolinate Chemical Properties

Melting point:
41-42°C
Boiling point:
302.7±22.0 °C(Predicted)
Density 
1.501±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-0.89±0.10(Predicted)
form 
solid
color 
Off-white
CAS DataBase Reference
21190-88-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
HS Code 
2933399990
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Ethyl 6-bromopicolinate Usage And Synthesis

Uses

ethyl 6-bromopicolinate is a model compound for the preliminary screening of dimerization reaction.

Preparation

Ethyl 6-bromopicolinate was prepared by monolithiation of 2,6-dibromopyridine followed by a reaction with ethyl formate and subsequently by a reaction with iodine in ethanol (Scheme 57). This three-step procedure furnished the required ethyl 6-bromopicolinate in 45% yield.

Synthesis of Ethyl 6-bromopicolinate

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