4-hydroxy Hexenal Chemical Properties

Boiling point:

89-90 °C(Press: 2 Torr)

Density 

0.980±0.06 g/cm3(Predicted)

storage temp. 

Store at -80°C

solubility 

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml

pka

13.18±0.20(Predicted)

4-hydroxy Hexenal Usage And Synthesis

Description

4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA.

Uses

(E)-4-Hydroxy Hexenal is a 4-hydroxyalkenals that induces genotoxic effects in the micromolar range.

Definition

ChEBI: 4-hydroxyhexenal is a fatty aldehyde.

References

[1] FREDERIK J.G.M. VAN KUIJK  Edward A D  Laura L Holte. 4-Hydroxyhexenal: A lipid peroxidation product derived from oxidized docosahexaenoic acid[J]. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990, 1043 1: Pages 116-118. DOI: 10.1016/0005-2760(90)90118-h
[2] VANKUIJK F.J.G.M. Quantitative Measurement of 4-Hydroxyalkenals in Oxidized Low-Density Lipoprotein by Gas Chromatography-Mass Spectrometry[J]. Analytical biochemistry, 1995, 224 1: Pages 420-424. DOI: 10.1006/abio.1995.1060