SCH 446132 Chemical Properties

Boiling point:

743.0±70.0 °C(Predicted)

Density 

1.62±0.1 g/cm3(Predicted)

pka

14.51±0.10(Predicted)

form 

Solid

color 

White to off-white

SCH 446132 Usage And Synthesis

Uses

Treatment of erectile dysfunction (phosphodiesterase (PDE) 5 isoenzyme inhibitor).

Uses

This product is Informer compound X12 of the Aryl Halide Chemistry Informer Library developed by chemists at Merck & Co., Inc., Kenilworth, NJ, U.S.., Inc., Kenilworth, NJ, U.S., which contains 18 drug-like molecules representative of those encountered in complex synthesis. By screening a new reaction against the Informer Library, chemists can directly compare and analyze a reactions′s successes and shortcomings among different methods and various research teams. It may also be used to faciliate deeper method development for performance or utility.

General Description

Dasantafil (SCH-446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to in genitourinary disorders and study erectile dysfunction.