1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[(2S)-4-(3-chlorophenyl)-2-methyl-1-piperazinyl]propyl]- Chemical Properties

Boiling point:

531.7±60.0 °C(Predicted)

Density 

1.31±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

7.93±0.10(Predicted)

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[(2S)-4-(3-chlorophenyl)-2-methyl-1-piperazinyl]propyl]- Usage And Synthesis

Uses

α1 adrenoceptor-MO-1, an S enantiomer, has affinity at alpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.

IC 50

α adrenergic receptor

References

[1] Pharmacologically active enantiomers. WO 1995001354 A1