4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]-
4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]- Basic information
- Product Name:
- 4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]-
- Synonyms:
-
- -HSD1-IN-1
- 4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]-
- 11β-HSD1-IN-1
- 11β-HSD-1-IN-1,11βHSD1IN1,11β HSD1 IN 1
- 11β-HSD1-IN-1, 10 mM in DMSO
- CAS:
- 1203956-47-1
- MF:
- C18H14ClF4N3O
- MW:
- 399.77
- Mol File:
- 1203956-47-1.mol
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4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]- Chemical Properties
- Boiling point:
- 507.3±60.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 1.38±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]- Usage And Synthesis
Description
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain.
References
[1]. THERAPEUTIC AGENT FOR PAIN. WO2012033070A1
4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]-Supplier
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