Basic information Safety Supplier Related

mPEG4-Hydrazide

Basic information Safety Supplier Related

mPEG4-Hydrazide Basic information

Product Name:
mPEG4-Hydrazide
Synonyms:
  • 4,7,10,13,16-Pentaoxaheptadecanoic acid, hydrazide
CAS:
1449390-65-1
MF:
C12H26N2O6
MW:
294.34
Mol File:
1449390-65-1.mol
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mPEG4-Hydrazide Chemical Properties

Boiling point:
443.9±40.0 °C(Predicted)
Density 
1.098±0.06 g/cm3(Predicted)
pka
12.82±0.35(Predicted)
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mPEG4-Hydrazide Usage And Synthesis

Biological Activity

m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

mPEG4-HydrazideSupplier

ChemPep, Inc.
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TargetMol Chemicals Inc.
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9i LLC
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