mPEG4-Hydrazide
mPEG4-Hydrazide Basic information
- Product Name:
- mPEG4-Hydrazide
- Synonyms:
-
- 4,7,10,13,16-Pentaoxaheptadecanoic acid, hydrazide
- CAS:
- 1449390-65-1
- MF:
- C12H26N2O6
- MW:
- 294.34
- Mol File:
- 1449390-65-1.mol
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mPEG4-Hydrazide Chemical Properties
- Boiling point:
- 443.9±40.0 °C(Predicted)
- Density
- 1.098±0.06 g/cm3(Predicted)
- pka
- 12.82±0.35(Predicted)
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mPEG4-Hydrazide Usage And Synthesis
Biological Activity
m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
mPEG4-HydrazideSupplier
ChemPep, Inc.
- Tel
- +1 (888) 615-9178 / (561) 791-8787
- service@chempep.com
Xi'an Confluore Biological Technology Co., Ltd.
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
9i LLC
- Tel
- +18039569191
- MWan@NiNeiLab.com
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mPEG4-Hydrazide(1449390-65-1)Related Product Information
- MPEG12-Hydrazide
- MPEG5-Hydrazide
- MPEG24-Hydrazide
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid
- m-PEG4-Hydrazide
- 3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontanoic acid
- MPEG8-Hydrazide
- MPEG6-Hydrazide
- MPEG16-Hydrazide
- MPEG36-Hydrazide
- 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid