Basic information Safety Supplier Related

5(S)-HPEPE

Basic information Safety Supplier Related

5(S)-HPEPE Basic information

Product Name:
5(S)-HPEPE
Synonyms:
  • 5(S)-HPEPE
  • 5S-HYDROPEROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
  • NKXYOIJDQPQELO-GHWNLOBHSA-N
  • 6,8,11,14,17-Eicosapentaenoic acid, 5-hydroperoxy-, [S-(E,Z,Z,Z,Z)]- (9CI)
  • 5(S)HpEPE,5(S) HpEPE
CAS:
143292-98-2
MF:
C20H30O4
MW:
334.45
Mol File:
Mol File
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5(S)-HPEPE Chemical Properties

storage temp. 
Store at -20°C
solubility 
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
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5(S)-HPEPE Usage And Synthesis

Description

5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA.1 It is metabolized to LTA5, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

Definition

ChEBI: 5S-HpEPE is a HPETE.

References

1. Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid J. Ocul. Pharmacol. 3(4),349-356(1987).

5(S)-HPEPESupplier

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TargetMol Chemicals Inc.
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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