H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH
H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH Basic information
- Product Name:
- H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH
- Synonyms:
-
- TS1 (1016-1023) (HUMAN, BOVINE, MOUSE)
- THROMBOSPONDIN-1 (1016-1023) (HUMAN, BOVINE, MOUSE)
- ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS
- H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH
- Thrombospondin-1 (1016-1023)
- L-Lysine, L-arginyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-
- L-Arginyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-L-lysine
- Thrombospondin-1 (1016-1023) (human, bovine, mouse), 10 mM in DMSO
- CAS:
- 149234-04-8
- MF:
- C56H81N13O10S
- MW:
- 1128.39
- Mol File:
- Mol File
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H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH Chemical Properties
- storage temp.
- -15°C
- form
- Solid
- color
- White to off-white
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H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH Usage And Synthesis
Uses
Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1].
References
[1] Chih-Jian Lih, et al. Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev. 2006 Aug 1;20(15):2082-95. DOI:10.1101/gad.1441306
[2] U Johansson, et al. CD47 ligation induces a rapid caspase-independent apoptosis-like cell death in human monocytes and dendritic cells. Scand J Immunol. 2004 Jan;59(1):40-9. DOI:10.1111/j.0300-9475.2004.01355.x
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