LAU159
LAU159 Basic information
- Product Name:
- LAU159
- Synonyms:
-
- LAU159
- CS-2770
- LAU159;LAU-159;LAU 159
- 3H-Pyrazolo[4,3-c]quinolin-3-one, 8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-
- 8-Chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one
- γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,GABA Receptor,LAU 159,inhibit,LAU159,Inhibitor,LAU-159
- 8-chloro-2-(3-methoxyphenyl)-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one
- LAU159 (LAU 159)
- CAS:
- 2055050-87-6
- MF:
- C17H12ClN3O2
- MW:
- 325.75
- Mol File:
- 2055050-87-6.mol
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LAU159 Chemical Properties
- Boiling point:
- 473.8±55.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A crystalline solid
- pka
- 6.26±0.20(Predicted)
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LAU159 Usage And Synthesis
Uses
LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].
References
[1] Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169(2):371-83. DOI:10.1111/bph.12151
LAU159Supplier
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696，15000506266 15000506266
ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Shanghai Chaolan Chemical Technology Center
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- 021-QQ：65489617 15618227136
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Chuzhou KeMail Chemical Technology Co., Ltd
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- 0550-5196001 15000891977
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Twochem Co.Ltd.
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- 021-58111628 15800915896
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