D-[UL-13C6]FRUCTOSE Chemical Properties

Melting point:

119-122 °C (dec.) (lit.)

storage temp. 

Store at -20°C

solubility 

DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

color 

White to off-white

optical activity

[α]20/D -93.5°, c = 2 in H2O (trace NH4OH)

CAS Number Unlabeled

57-48-7

CAS Number Unlabeled

57-48-7

Safety Information

WGK Germany 

3

D-[UL-13C6]FRUCTOSE Usage And Synthesis

Description

D-Fructose-¹³C₆ is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine. It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate , which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet. Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity.

Uses

Isotope labelled D-Fructose (F792500), a monosaccharide that naturally occurs in large number of fruits and plants.

References

[1] M CHEN  R L W. Metabolism of D-fructose.[J]. Advances in carbohydrate chemistry and biochemistry, 1977, 34: 265-343.
[2] TRAN C. Inborn Errors of Fructose Metabolism. What Can We Learn from Them?[J]. Nutrients, 2017, 9 4. DOI: 10.3390/nu9040356
[3] LUC TAPPY  Kim A L. Metabolic effects of fructose and the worldwide increase in obesity.[J]. Physiological reviews, 2010, 90 1: 23-46. DOI: 10.1152/physrev.00019.2009

D-[UL-13C6]FRUCTOSE(201595-65-5)Related Product Information

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