LMT-28 Chemical Properties

Boiling point:

452.9±38.0 °C(Predicted)

Density 

1.065±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

100 mg/mL in DMSO (321.11 mM),

pka

13.97±0.20(Predicted)

form 

oil

color 

colorless to light yellow, oil

Water Solubility 

< 0.1 mg/mL Water (insoluble)

LMT-28 Usage And Synthesis

Biochem/physiol Actions

LMT-28 is a derivative of oxazolidinone. It has the ability to repress the activation of signal transducer and activator of transcription 3 (STAT3) stimulated by interleukin 6 (IL-6). Orally administered LMT-28 reduced arthritis and acute pancreatitis stimulated by collagen in mice pathologic models.