Sparstolonin B Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO : 10 mg/mL (Need ultrasonic and warming)

form 

powder

color 

white to beige

Sparstolonin B Usage And Synthesis

Biochem/physiol Actions

Sparstolonin B (SsnB) is a polyphenol. It has a structural features similar to xanthone and isocoumarin. SsnB exerts anti-inflammatory properties on mouse and human macrophages. SsnB can significantly reduce hypoxia–reoxygenation-induced inflammation of cardiomyocytes by blocking extracellular signal-regulated protein kinase (ERK1/2) and c-jun N-terminal kinases (JNK) signaling pathways. Thus, SsnB acts as a potent therapeutic for the treatment of myocardial ischemia–reperfusion (MIR) injury.